ABOUT US
About Company
Investors
CSR
PIPELINE
CDP
Product
Publication
NEWS
Corporate News
Media Reports
CAREER
Talents Value
Talents Acquisition
CONTACTS
中文
/
en
ABOUT US
About Company
Investors
CSR
PIPELINE
CDP
Product
Publication
NEWS
Corporate News
Media Reports
CAREER
Talents Value
Talents Acquisition
CONTACTS
Phone: +86 21 63862192
Mailbox: info@alphabiopharma.com
Shanghai: Unit 02-05, 11/F, East Tower, Raffles City The Bund No.1089 Dong Daming Road, Shanghai 200082, China
Beijing: Room 2512, The Place Tower, No. 9 Guanghua Road, Chaoyang District, Beijing
Share :
PIPELINE
Publication
CDP
Product
Publication
EGFR-TKI
21
2023.09
Efficacy, safety and dose selection of AZD3759 in patients with untreated EGFR-mutated non-small-cell lung cancer and central nervous system metastases in China (CTONG1702-Arm 8): a multi-center, single-arm, phase 2 trial
The Lancet, Si-Yang Maggie Liu et al
01
2018.03
Enhanced efficacy of AZD3759 and radiation on brain metastasis from EGFR mutant non-small cell lung cancer
Int J Cancer, Xue Li et al
19
2017.10
Activity and safety of AZD3759 in EGFR-mutant non-small-cell lung cancer with CNS metastases (BLOOM): a phase 1, open-label, dose-escalation and dose-expansion study
Lancet Respir Med, Myung-Ju Ahn et al
07
2016.12
AZD3759, a BBB-penetrating EGFR inhibitor for the treatment of EGFR mutant NSCLC with CNS metastases
Sci Transl Med, Zhenfan Yang et al
09
2015.10
Discovery and Evaluation of Clinical Candidate AZD3759, a Potent, Oral Active, Central Nervous System-Penetrant, Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor
J Med Chem, Qingbei Zeng et al
Cell Therapy
23
2022.02
Hematopoietic cell transplantation donor-derived memory-like NK cells functionally persist after transfer into patients with leukemia
Science Translational Medicine, Berrien-Elliot et al
06
2021.12
Donor Memory-like NK cells Persist and Induce Remissions in Pediatric Patients with Relapsed AML after Transplant
Blood, Bednarski et al
09
2021.07
A Fusion Protein Complex that Combines IL-12, IL-15, and IL-18 Signaling to Induce Memory-Like NK Cells for Cancer Immunotherapy
Cancer Immunol Res, Becker-Hapak et al
29
2021.06
Memory-like Differentiation Enhances NK Cell Responses to Melanoma
Clin Cancer Res, Martin et al
10
2020.12
Multidimensional Analyses of Donor Memory-Like NK Cells Reveal New Associations with Response after Adoptive Immunotherapy for Leukemia
Cancer Discovery, Berrien-Elliott et al
12
2020.11
CAR-modified memory-like NK cells exhibit potent responses to NK-resistant lymphomas
Blood Gang, et al
01
2020.10
Memory-like natural killer cells for cancer immunotherapy
Seminars in Hematology, Gang et al
18
2019.10
Chimeric antigen receptor T cells (CAR-T) for the treatment of T-cell malignancies
Best Pract Res Clin Haematol, Mathew Cooper et al
12
2018.10
CAR T-cells for T-cell malignancies: challenges in distinguishing between therapeutic, normal, and neoplastic T-cells
Leukemia, Alcantara et al
20
2018.02
An “off-the-shelf” fratricide-resistant CAR-T for the treatment of T cell hematologic malignancies
Leukemia, Cooper et al
01
2017.03
Cytokine-Induced Memory-Like Differentiation Enhances Unlicensed Natural Killer Cell Antileukemia and FcγRIIIa-Triggered Responses
Biol Blood Marrow Transplant, Wagner et al
21
2016.09
Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukemia
Science Translational Medicine, Romee et al
01
2014.04
Preactivation with IL-12, IL-15, and IL-18 Induces CD25 and a Functional High-Affinity IL-2 Receptor on Human Cytokine-Induced Memory-like Natural Killer Cells
Biol Blood Marrow Transplant, Leong et al
06
2012.12
Cytokine activation induces human memory-like NK cells
Blood, Romme et al
